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Perlecan, A Multi-Functional, Cell-Instructive, Matrix-Stabilizing Proteoglycan With Roles in Tissue Development Has Relevance to Connective Tissue Repair and Regeneration

This review highlights the multifunctional properties of perlecan (HSPG2) and its potential roles in repair biology. Perlecan is ubiquitous, occurring in vascular, cartilaginous, adipose, lymphoreticular, bone and bone marrow stroma and in neural tissues. Perlecan has roles in angiogenesis, tissue d...

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Detalles Bibliográficos
Autores principales: Hayes, Anthony J., Farrugia, Brooke L., Biose, Ifechukwude J., Bix, Gregory J., Melrose, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010944/
https://www.ncbi.nlm.nih.gov/pubmed/35433700
http://dx.doi.org/10.3389/fcell.2022.856261