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An unexpected role for PD-L1 in front–rear polarization and directional migration

Programmed cell death-ligand 1 (PD-L1)–mediated T cell inhibition through PD-1 is a key checkpoint frequently exploited by tumors to evade immunity. In this issue, Wang et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202108083) reveal an unexpected role for PD-L1 in promoting tumor cell fron...

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Detalles Bibliográficos
Autores principales: Sánchez-Álvarez, Miguel, del Pozo, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011200/
https://www.ncbi.nlm.nih.gov/pubmed/35416931
http://dx.doi.org/10.1083/jcb.202203137