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The development of a redox-sensitive curcumin conjugated chitosan oligosaccharide nanocarrier for the efficient delivery of docetaxel to glioma cells

BACKGROUND: A redox-sensitive nanoscale delivery system was developed, based on the hydrophilic chitosan oligosaccharide-ss-hydrophobic curcumin conjugate (CSO-ss-CUR) loaded with docetaxel (DTX), for the targeting and synergistic treatment of gliomas. METHODS: Redox-sensitive nanoparticles were loa...

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Detalles Bibliográficos
Autores principales: Liu, Chunxi, Gao, Yuan, Zhao, Lixia, Wang, Rui, Xie, Fei, Zhai, Guangxi, Liu, Anchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011229/
https://www.ncbi.nlm.nih.gov/pubmed/35433960
http://dx.doi.org/10.21037/atm-22-288