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The HOPS tethering complex is required to maintain signaling endosome identity and TORC1 activity

The endomembrane system of eukaryotic cells is essential for cellular homeostasis during growth and proliferation. Previous work showed that a central regulator of growth, namely the target of rapamycin complex 1 (TORC1), binds both membranes of vacuoles and signaling endosomes (SEs) that are distin...

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Detalles Bibliográficos
Autores principales: Gao, Jieqiong, Nicastro, Raffaele, Péli-Gulli, Marie-Pierre, Grziwa, Sophie, Chen, Zilei, Kurre, Rainer, Piehler, Jacob, De Virgilio, Claudio, Fröhlich, Florian, Ungermann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011323/
https://www.ncbi.nlm.nih.gov/pubmed/35404387
http://dx.doi.org/10.1083/jcb.202109084