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Dihuang-Yinzi Alleviates Cognition Deficits via Targeting Energy-Related Metabolism in an Alzheimer Mouse Model as Demonstrated by Integration of Metabolomics and Network Pharmacology

Energy metabolism disturbance and the consequent reactive oxygen species (ROS) overproduction play a key and pathogenic role in the onset and progression of Alzheimer’s disease (AD). Dihuang-Yinzi (DHYZ) is a traditional Chinese herbal prescription clinically applied to treat AD and other neurodegen...

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Detalles Bibliográficos
Autores principales: Han, Guanghui, Zhen, Weizhe, Dai, Yuan, Yu, Hongni, Li, Dongyue, Ma, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011333/
https://www.ncbi.nlm.nih.gov/pubmed/35431901
http://dx.doi.org/10.3389/fnagi.2022.873929