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Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes

[Image: see text] Chronically elevated circulating fatty acid levels promote lipid accumulation in nonadipose tissues and cause lipotoxicity. Adipose triglyceride lipase (ATGL) critically determines the release of fatty acids from white adipose tissue, and accumulating evidence suggests that inactiv...

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Detalles Bibliográficos
Autores principales: Grabner, Gernot F., Guttenberger, Nikolaus, Mayer, Nicole, Migglautsch-Sulzer, Anna K., Lembacher-Fadum, Christian, Fawzy, Nermeen, Bulfon, Dominik, Hofer, Peter, Züllig, Thomas, Hartig, Lennart, Kulminskaya, Natalia, Chalhoub, Gabriel, Schratter, Margarita, Radner, Franz P. W., Preiss-Landl, Karina, Masser, Sarah, Lass, Achim, Zechner, Rudolf, Gruber, Karl, Oberer, Monika, Breinbauer, Rolf, Zimmermann, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011347/
https://www.ncbi.nlm.nih.gov/pubmed/35362954
http://dx.doi.org/10.1021/jacs.1c10836