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Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes
[Image: see text] Chronically elevated circulating fatty acid levels promote lipid accumulation in nonadipose tissues and cause lipotoxicity. Adipose triglyceride lipase (ATGL) critically determines the release of fatty acids from white adipose tissue, and accumulating evidence suggests that inactiv...
Autores principales: | Grabner, Gernot F., Guttenberger, Nikolaus, Mayer, Nicole, Migglautsch-Sulzer, Anna K., Lembacher-Fadum, Christian, Fawzy, Nermeen, Bulfon, Dominik, Hofer, Peter, Züllig, Thomas, Hartig, Lennart, Kulminskaya, Natalia, Chalhoub, Gabriel, Schratter, Margarita, Radner, Franz P. W., Preiss-Landl, Karina, Masser, Sarah, Lass, Achim, Zechner, Rudolf, Gruber, Karl, Oberer, Monika, Breinbauer, Rolf, Zimmermann, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011347/ https://www.ncbi.nlm.nih.gov/pubmed/35362954 http://dx.doi.org/10.1021/jacs.1c10836 |
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