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Unexpected Methyllanthionine Stereochemistry in the Morphogenetic Lanthipeptide SapT

[Image: see text] Lanthipeptides are polycyclic peptides characterized by the presence of lanthionine (Lan) and/or methyllanthionine (MeLan). They are members of the ribosomally synthesized and post-translationally modified peptides (RiPPs). The stereochemical configuration of (Me)Lan cross-links is...

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Detalles Bibliográficos
Autores principales: Sarksian, Raymond, Hegemann, Julian D., Simon, Max A., Acedo, Jeella Z., van der Donk, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011353/
https://www.ncbi.nlm.nih.gov/pubmed/35352944
http://dx.doi.org/10.1021/jacs.2c00517