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Designed SARS‐CoV‐2 receptor binding domain variants form stable monomers

The receptor binding domain (RBD) of the SARS‐CoV‐2 spike (S)‐protein is a prime target of virus‐neutralizing antibodies present in convalescent sera of COVID‐19 patients and thus is considered a key antigen for immunosurveillance studies and vaccine development. Although recombinant expression of R...

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Detalles Bibliográficos
Autores principales: Klausberger, Miriam, Kienzl, Nikolaus F., Stadlmayr, Gerhard, Grünwald‐Gruber, Clemens, Laurent, Elisabeth, Stadlbauer, Katharina, Stracke, Florian, Vierlinger, Klemens, Hofner, Manuela, Manhart, Gabriele, Gerner, Wilhelm, Grebien, Florian, Weinhäusel, Andreas, Mach, Lukas, Wozniak‐Knopp, Gordana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011732/
https://www.ncbi.nlm.nih.gov/pubmed/35078277
http://dx.doi.org/10.1002/biot.202100422