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mbDenoise: microbiome data denoising using zero-inflated probabilistic principal components analysis
The analysis of microbiome data has several technical challenges. In particular, count matrices contain a large proportion of zeros, some of which are biological, whereas others are technical. Furthermore, the measurements suffer from unequal sequencing depth, overdispersion, and data redundancy. Th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011970/ https://www.ncbi.nlm.nih.gov/pubmed/35422001 http://dx.doi.org/10.1186/s13059-022-02657-3 |