MAVE-NN: learning genotype-phenotype maps from multiplex assays of variant effect

Multiplex assays of variant effect (MAVEs) are a family of methods that includes deep mutational scanning experiments on proteins and massively parallel reporter assays on gene regulatory sequences. Despite their increasing popularity, a general strategy for inferring quantitative models of genotype...

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Detalles Bibliográficos
Autores principales: Tareen, Ammar, Kooshkbaghi, Mahdi, Posfai, Anna, Ireland, William T., McCandlish, David M., Kinney, Justin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011994/
https://www.ncbi.nlm.nih.gov/pubmed/35428271
http://dx.doi.org/10.1186/s13059-022-02661-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011994/
https://www.ncbi.nlm.nih.gov/pubmed/35428271
http://dx.doi.org/10.1186/s13059-022-02661-7

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