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MAVE-NN: learning genotype-phenotype maps from multiplex assays of variant effect
Multiplex assays of variant effect (MAVEs) are a family of methods that includes deep mutational scanning experiments on proteins and massively parallel reporter assays on gene regulatory sequences. Despite their increasing popularity, a general strategy for inferring quantitative models of genotype...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011994/ https://www.ncbi.nlm.nih.gov/pubmed/35428271 http://dx.doi.org/10.1186/s13059-022-02661-7 |