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Short-term senolytic treatment: a paradigm to promote fracture repair during aging

Increased age is blamed for a wide range of bone physiological changes, and although the underlying mechanisms affecting the decreased capacity for fracture healing are not fully understood, they are clearly linked to changes at the cellular level. Recent evidence suggests potential roles of senesce...

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Detalles Bibliográficos
Autores principales: Beerman, Isabel, Basisty, Nathan, de Cabo, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012278/
https://www.ncbi.nlm.nih.gov/pubmed/35426369
http://dx.doi.org/10.1172/JCI158871