Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease

The respiratory tract surface is protected from inhaled pathogens by a secreted layer of mucus rich in mucin glycoproteins. Abnormal mucus accumulation is a cardinal feature of chronic respiratory diseases, but the relationship between mucus and pathogens during exacerbations is poorly understood. W...

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Detalles Bibliográficos
Autores principales: Singanayagam, Aran, Footitt, Joseph, Marczynski, Matthias, Radicioni, Giorgia, Cross, Michael T., Finney, Lydia J., Trujillo-Torralbo, Maria-Belen, Calderazzo, Maria, Zhu, Jie, Aniscenko, Julia, Clarke, Thomas B., Molyneaux, Philip L., Bartlett, Nathan W., Moffatt, Miriam F., Cookson, William O., Wedzicha, Jadwiga, Evans, Christopher M., Boucher, Richard C., Kesimer, Mehmet, Lieleg, Oliver, Mallia, Patrick, Johnston, Sebastian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012283/
https://www.ncbi.nlm.nih.gov/pubmed/35239513
http://dx.doi.org/10.1172/JCI120901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012283/
https://www.ncbi.nlm.nih.gov/pubmed/35239513
http://dx.doi.org/10.1172/JCI120901

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