Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy

Interleukin-10 (IL-10) is an immunosuppressive cytokine that signals through STAT3 to regulate T follicular helper (Tfh) cell differentiation and germinal center formation. In SIV-infected macaques, levels of IL-10 in plasma and lymph nodes (LNs) were induced by infection and not normalized with ant...

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Detalles Bibliográficos
Autores principales: Harper, Justin, Ribeiro, Susan P., Chan, Chi Ngai, Aid, Malika, Deleage, Claire, Micci, Luca, Pino, Maria, Cervasi, Barbara, Raghunathan, Gopalan, Rimmer, Eric, Ayanoglu, Gulesi, Wu, Guoxin, Shenvi, Neeta, Barnard, Richard J.O., Del Prete, Gregory Q., Busman-Sahay, Kathleen, Silvestri, Guido, Kulpa, Deanna A., Bosinger, Steven E., Easley, Kirk A., Howell, Bonnie J., Gorman, Dan, Hazuda, Daria J., Estes, Jacob D., Sekaly, Rafick-Pierre, Paiardini, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012284/
https://www.ncbi.nlm.nih.gov/pubmed/35230978
http://dx.doi.org/10.1172/JCI155251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012284/
https://www.ncbi.nlm.nih.gov/pubmed/35230978
http://dx.doi.org/10.1172/JCI155251

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