Aberrant miR-339-5p/neuronatin signaling causes prodromal neuronal calcium dyshomeostasis in mutant presenilin mice

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Mushroom spine loss and calcium dyshomeostasis are early hallmark events of age-related neurodegeneration, such as Alzheimer’s disease (AD), that are connected with neuronal hyperactivity in early pathology of cognitive brain areas. However, it remains elusive how these key events are triggered at t...

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Detalles Bibliográficos
Autores principales: Zou, Hao-Yu, Guo, Lin, Zhang, Bei, Chen, Si, Wu, Xin-Rong, Liu, Xian-Dong, Xu, Xin-Yu, Li, Bin-Yin, Chen, Shengdi, Xu, Nan-Jie, Sun, Suya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012292/
https://www.ncbi.nlm.nih.gov/pubmed/35426376
http://dx.doi.org/10.1172/JCI149160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012292/
https://www.ncbi.nlm.nih.gov/pubmed/35426376
http://dx.doi.org/10.1172/JCI149160

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