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Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design

BACKGROUND: The Ilheus virus (ILHV) is an encephalitis associated arthropod-borne flavivirus. It was first identified in Ilheus City in the northeast Brazil before spreading to a wider geographic range. No specific vaccines or drugs are currently available for the treatment of ILHV infections. The I...

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Detalles Bibliográficos
Autores principales: Wang, De-Ping, Wang, Mei-Yue, Li, Yong-Mei, Shu, Wen, Cui, Wen, Jiang, Fang-Ying, Zhou, Xin, Wang, Wen-Ming, Cao, Ji-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012436/
https://www.ncbi.nlm.nih.gov/pubmed/35428322
http://dx.doi.org/10.1186/s13578-022-00777-8