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Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

Intestinal epithelial cells (IECs) have long been understood to express high levels of major histocompatibility complex class II (MHC class II) molecules but are not considered canonical antigen-presenting cells, and the impact of IEC-MHC class II signaling on gut homeostasis remains enigmatic. As I...

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Detalles Bibliográficos
Autores principales: Stephens, W. Zac, Kubinak, Jason L., Ghazaryan, Arevik, Bauer, Kaylyn M., Bell, Rickesha, Buhrke, Kate, Chiaro, Tyson R., Weis, Allison M., Tang, William W., Monts, Josh K., Soto, Ray, Ekiz, H. Atakan, O’Connell, Ryan M., Round, June L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012449/
https://www.ncbi.nlm.nih.gov/pubmed/34731608
http://dx.doi.org/10.1016/j.celrep.2021.109916