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Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition
Intestinal epithelial cells (IECs) have long been understood to express high levels of major histocompatibility complex class II (MHC class II) molecules but are not considered canonical antigen-presenting cells, and the impact of IEC-MHC class II signaling on gut homeostasis remains enigmatic. As I...
Autores principales: | Stephens, W. Zac, Kubinak, Jason L., Ghazaryan, Arevik, Bauer, Kaylyn M., Bell, Rickesha, Buhrke, Kate, Chiaro, Tyson R., Weis, Allison M., Tang, William W., Monts, Josh K., Soto, Ray, Ekiz, H. Atakan, O’Connell, Ryan M., Round, June L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012449/ https://www.ncbi.nlm.nih.gov/pubmed/34731608 http://dx.doi.org/10.1016/j.celrep.2021.109916 |
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