Egr1 is a 3D matrix–specific mediator of mechanosensitive stem cell lineage commitment

While extracellular matrix (ECM) mechanics strongly regulate stem cell commitment, the field’s mechanistic understanding of this phenomenon largely derives from simplified two-dimensional (2D) culture substrates. Here, we found a 3D matrix–specific mechanoresponsive mechanism for neural stem cell (N...

Descripción completa

Detalles Bibliográficos
Autores principales: Baek, Jieung, Lopez, Paola A., Lee, Sangmin, Kim, Taek-Soo, Kumar, Sanjay, Schaffer, David V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012469/
https://www.ncbi.nlm.nih.gov/pubmed/35427160
http://dx.doi.org/10.1126/sciadv.abm4646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012469/
https://www.ncbi.nlm.nih.gov/pubmed/35427160
http://dx.doi.org/10.1126/sciadv.abm4646

Ejemplares similares