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Egr1 is a 3D matrix–specific mediator of mechanosensitive stem cell lineage commitment

While extracellular matrix (ECM) mechanics strongly regulate stem cell commitment, the field’s mechanistic understanding of this phenomenon largely derives from simplified two-dimensional (2D) culture substrates. Here, we found a 3D matrix–specific mechanoresponsive mechanism for neural stem cell (N...

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Detalles Bibliográficos
Autores principales:	Baek, Jieung, Lopez, Paola A., Lee, Sangmin, Kim, Taek-Soo, Kumar, Sanjay, Schaffer, David V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012469/ https://www.ncbi.nlm.nih.gov/pubmed/35427160 http://dx.doi.org/10.1126/sciadv.abm4646

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