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Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching
Vascular smooth muscle cells (VSMCs) play a central role in the progression of atherosclerosis, where they switch from a contractile to a synthetic phenotype. Because of their role as risk factors for atherosclerosis, we sought here to systematically study the impact of matrix stiffness and (hemodyn...
Autores principales: | Swiatlowska, Pamela, Sit, Brian, Feng, Zhen, Marhuenda, Emilie, Xanthis, Ioannis, Zingaro, Simona, Ward, Matthew, Zhou, Xinmiao, Xiao, Qingzhong, Shanahan, Cathy, Jones, Gareth E., Yu, Cheng-han, Iskratsch, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012473/ https://www.ncbi.nlm.nih.gov/pubmed/35427166 http://dx.doi.org/10.1126/sciadv.abm3471 |
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