Identification of Natural Products as SENP2 Inhibitors for Targeted Therapy in Heart Failure

Aims: Sentrin-specific protease -2 (SENP2) is involved in deSUMOylation. Increased deSUMOylation in murine hearts by SENP2 upregulation resulted in cardiac dysfunction and congenital heart defects. Natural compounds via regulating cell proliferation and survival, induce cell cycle cessation, cell de...

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Detalles Bibliográficos
Autores principales: Taghvaei, Somayye, Sabouni, Farzaneh, Minuchehr, Zarrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012495/
https://www.ncbi.nlm.nih.gov/pubmed/35431915
http://dx.doi.org/10.3389/fphar.2022.817990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012495/
https://www.ncbi.nlm.nih.gov/pubmed/35431915
http://dx.doi.org/10.3389/fphar.2022.817990

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