CRISPRi for specific inhibition of miRNA clusters and miRNAs with high sequence homology

miRNAs form a class of noncoding RNAs, involved in post-transcriptional regulation of gene expression, broadly studied for their involvement in physiological and pathological context. Inhibition of mature miRNA transcripts, commonly used in miRNA loss-of-function experiments, may not be specific in...

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Detalles Bibliográficos
Autores principales: Drobna-Śledzińska, Monika, Maćkowska-Maślak, Natalia, Jaksik, Roman, Dąbek, Paulina, Witt, Michał, Dawidowska, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012752/
https://www.ncbi.nlm.nih.gov/pubmed/35428787
http://dx.doi.org/10.1038/s41598-022-10336-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012752/
https://www.ncbi.nlm.nih.gov/pubmed/35428787
http://dx.doi.org/10.1038/s41598-022-10336-3

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