Cargando…
Serotonergic system in vivo with [(11)C]DASB PET scans in GTP-cyclohydrolase deficient dopa-responsive dystonia patients
GTP-cyclohydrolase deficiency in dopa-responsive dystonia (DRD) patients impairs the biosynthesis of dopamine, but also of serotonin. The high prevalence of non-motor symptoms suggests involvement of the serotonergic pathway. Our study aimed to investigate the serotonergic system in vivo in the brai...
Autores principales: | Timmers, Elze R., Peretti, Débora E., Smit, Marenka, de Jong, Bauke M., Dierckx, Rudi A. J. O., Kuiper, Anouk, de Koning, Tom J., Vállez García, David, Tijssen, Marina A. J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012759/ https://www.ncbi.nlm.nih.gov/pubmed/35428769 http://dx.doi.org/10.1038/s41598-022-10067-5 |
Ejemplares similares
-
Relationships between Serotonin Transporter Binding in the Raphe Nuclei, Basal Ganglia, and Hippocampus with Clinical Symptoms in Cervical Dystonia: A [(11)C]DASB Positron Emission Tomography Study
por: Smit, Marenka, et al.
Publicado: (2018) -
GTP Cyclohydrolase I and Tyrosine Hydroxylase Gene Mutations in Familial and Sporadic Dopa-Responsive Dystonia Patients
por: Cai, Chunyou, et al.
Publicado: (2013) -
Dopa-Responsive Dystonia in Han Chinese Patients: One Novel Heterozygous Mutation in GTP Cyclohydrolase 1 (GCH1) and Three Known Mutations in TH
por: Yang, Kunfang, et al.
Publicado: (2018) -
Methylation of the serotonin reuptake transporter gene and non-motor symptoms in dystonia patients
por: Timmers, Elze R., et al.
Publicado: (2022) -
Parkinson’s disease in GTP cyclohydrolase 1 mutation carriers
por: Mencacci, Niccolò E., et al.
Publicado: (2014)