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(89)Zr-PET imaging to predict tumor uptake of (177)Lu-NNV003 anti-CD37 radioimmunotherapy in mouse models of B cell lymphoma

[(177)Lu]Lu-DOTA-NNV003, a radioimmunoconjugate targeting CD37, is developed as novel radioimmunotherapy (RIT) treatment for patients with B cell non-Hodgkin’s lymphoma (NHL). Since patients are at risk for developing hematological toxicities due to CD37 expression on normal B cells, we aimed to dev...

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Detalles Bibliográficos
Autores principales: Giesen, Danique, Hooge, Marjolijn N. Lub-de, Nijland, Marcel, Heyerdahl, Helen, Dahle, Jostein, de Vries, Elisabeth G. E., Pool, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012778/
https://www.ncbi.nlm.nih.gov/pubmed/35428777
http://dx.doi.org/10.1038/s41598-022-10139-6