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KDM5B promotes tumorigenesis of Ewing sarcoma via FBXW7/CCNE1 axis
Ewing sarcoma (EwS) is an aggressive tumor that affects children and young adults. Patients with relapsed/refractory diseases have limited treatment options. Targeting the driver fusion oncoproteins of EwS remains a technical problem. Epigenetic mechanisms have been pointed out as key players and al...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012801/ https://www.ncbi.nlm.nih.gov/pubmed/35428764 http://dx.doi.org/10.1038/s41419-022-04800-1 |