KDM5B promotes tumorigenesis of Ewing sarcoma via FBXW7/CCNE1 axis

Ewing sarcoma (EwS) is an aggressive tumor that affects children and young adults. Patients with relapsed/refractory diseases have limited treatment options. Targeting the driver fusion oncoproteins of EwS remains a technical problem. Epigenetic mechanisms have been pointed out as key players and al...

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Detalles Bibliográficos
Autores principales: Chen, Binbin, Chen, Huimou, Lu, Suying, Zhu, Xiaoqin, Que, Yi, Zhang, Yu, Huang, Junting, Zhang, Li, Sun, Feifei, Wang, Juan, Zhu, Jia, Zhen, Zijun, Zhang, Yizhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012801/
https://www.ncbi.nlm.nih.gov/pubmed/35428764
http://dx.doi.org/10.1038/s41419-022-04800-1

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