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The nuclear receptor REV-ERBα is implicated in the alteration of β-cell autophagy and survival under diabetogenic conditions

Pancreatic β-cell failure in type 2 diabetes mellitus (T2DM) is associated with impaired regulation of autophagy which controls β-cell development, function, and survival through clearance of misfolded proteins and damaged organelles. However, the mechanisms responsible for defective autophagy in T2...

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Detalles Bibliográficos
Autores principales: Brown, Matthew R., Laouteouet, Damien, Delobel, Morgane, Villard, Orianne, Broca, Christophe, Bertrand, Gyslaine, Wojtusciszyn, Anne, Dalle, Stéphane, Ravier, Magalie A., Matveyenko, Aleksey V., Costes, Safia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012816/
https://www.ncbi.nlm.nih.gov/pubmed/35428762
http://dx.doi.org/10.1038/s41419-022-04767-z