The lactate sensor GPR81 regulates glycolysis and tumor growth of breast cancer

Metabolic reprogramming is a malignant phenotype of cancer. Cancer cells utilize glycolysis to fuel rapid proliferation even in the presence of oxygen, and elevated glycolysis is coupled to lactate fermentation in the cancer microenvironment. Although lactate has been recognized as a metabolic waste...

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Detalles Bibliográficos
Autores principales: Ishihara, Shota, Hata, Kenji, Hirose, Katsutoshi, Okui, Tatsuo, Toyosawa, Satoru, Uzawa, Narikazu, Nishimura, Riko, Yoneda, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012857/
https://www.ncbi.nlm.nih.gov/pubmed/35428832
http://dx.doi.org/10.1038/s41598-022-10143-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012857/
https://www.ncbi.nlm.nih.gov/pubmed/35428832
http://dx.doi.org/10.1038/s41598-022-10143-w

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