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srGAP2 deactivates RhoA to control the duration of thrombin-mediated endothelial permeability
The endothelial barrier is a tightly regulated gateway in the transport of material between circulation and the tissues. Inflammatory mediators such as thrombin are able to open paracellular spaces in the endothelial monolayer to allow the extravasation of plasma proteins and leukocytes. Here we sho...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Bioscientifica Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012936/ https://www.ncbi.nlm.nih.gov/pubmed/35441126 http://dx.doi.org/10.1530/VB-21-0012 |