Progerin mislocalizes myocardin-related transcription factor in Hutchinson–Guilford Progeria syndrome

Hutchinson–Guilford Progeria syndrome (HGPS) is a rare genetic disease of premature aging and early death due to cardiovascular disease. The arteries of HGPS children and mice are pathologically stiff, and HGPS mice also display reduced arterial contractility. We recently showed that reduced contrac...

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Detalles Bibliográficos
Autores principales: von Kleeck, Ryan, Castagnino, Paola, Assoian, Richard K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012937/
https://www.ncbi.nlm.nih.gov/pubmed/35441125
http://dx.doi.org/10.1530/VB-21-0018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012937/
https://www.ncbi.nlm.nih.gov/pubmed/35441125
http://dx.doi.org/10.1530/VB-21-0018

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