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Progerin mislocalizes myocardin-related transcription factor in Hutchinson–Guilford Progeria syndrome
Hutchinson–Guilford Progeria syndrome (HGPS) is a rare genetic disease of premature aging and early death due to cardiovascular disease. The arteries of HGPS children and mice are pathologically stiff, and HGPS mice also display reduced arterial contractility. We recently showed that reduced contrac...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Bioscientifica Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012937/ https://www.ncbi.nlm.nih.gov/pubmed/35441125 http://dx.doi.org/10.1530/VB-21-0018 |