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Phase I study of [(131)I] ICF01012, a targeted radionuclide therapy, in metastatic melanoma: MELRIV-1 protocol

BACKGROUND: Benzamide-based radioligands targeting melanin were first developed for imaging melanoma and then for therapeutic purpose with targeted radionuclide therapy (TRT). [(131)I]ICF01012 presents a highly favorable pharmacokinetics profile in vivo for therapy. Tumour growth reduction and incre...

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Detalles Bibliográficos
Autores principales: Thivat, Emilie, Rouanet, Jacques, Auzeloux, Philippe, Sas, Nicolas, Jouberton, Elodie, Levesque, Sophie, Billoux, Tommy, Mansard, Sandrine, Molnar, Ioana, Chanchou, Marion, Fois, Giovanna, Maigne, Lydia, Chezal, Jean-Michel, Miot-Noirault, Elisabeth, D’Incan, Michel, Durando, Xavier, Cachin, Florent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013026/
https://www.ncbi.nlm.nih.gov/pubmed/35428211
http://dx.doi.org/10.1186/s12885-022-09495-3