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Phase I study of [(131)I] ICF01012, a targeted radionuclide therapy, in metastatic melanoma: MELRIV-1 protocol
BACKGROUND: Benzamide-based radioligands targeting melanin were first developed for imaging melanoma and then for therapeutic purpose with targeted radionuclide therapy (TRT). [(131)I]ICF01012 presents a highly favorable pharmacokinetics profile in vivo for therapy. Tumour growth reduction and incre...
Autores principales: | Thivat, Emilie, Rouanet, Jacques, Auzeloux, Philippe, Sas, Nicolas, Jouberton, Elodie, Levesque, Sophie, Billoux, Tommy, Mansard, Sandrine, Molnar, Ioana, Chanchou, Marion, Fois, Giovanna, Maigne, Lydia, Chezal, Jean-Michel, Miot-Noirault, Elisabeth, D’Incan, Michel, Durando, Xavier, Cachin, Florent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013026/ https://www.ncbi.nlm.nih.gov/pubmed/35428211 http://dx.doi.org/10.1186/s12885-022-09495-3 |
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