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Variation in targetable genomic alterations in non-small cell lung cancer by genetic ancestry, sex, smoking history, and histology

BACKGROUND: Genomic alterations in 8 genes are now the targets of FDA-approved therapeutics in non-small cell lung cancer (NSCLC), but their distribution according to genetic ancestry, sex, histology, and smoking is not well established. METHODS: Using multi-institutional genetic testing data from G...

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Detalles Bibliográficos
Autores principales: Adib, Elio, Nassar, Amin H., Abou Alaiwi, Sarah, Groha, Stefan, Akl, Elie W., Sholl, Lynette M., Michael, Kesi S., Awad, Mark M., Jӓnne, Pasi A., Gusev, Alexander, Kwiatkowski, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013075/
https://www.ncbi.nlm.nih.gov/pubmed/35428358
http://dx.doi.org/10.1186/s13073-022-01041-x