Mitochondrial supplementation of Sus scrofa metaphase II oocytes alters DNA methylation and gene expression profiles of blastocysts

BACKGROUND: Mitochondrial DNA (mtDNA) copy number in oocytes correlates with oocyte quality and fertilisation outcome. The introduction of additional copies of mtDNA through mitochondrial supplementation of mtDNA-deficient Sus scrofa oocytes resulted in: (1) improved rates of fertilisation; (2) incr...

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Detalles Bibliográficos
Autores principales: Okada, Takashi, McIlfatrick, Stephen, Hin, Nhi, Aryamanesh, Nader, Breen, James, St. John, Justin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013150/
https://www.ncbi.nlm.nih.gov/pubmed/35428319
http://dx.doi.org/10.1186/s13072-022-00442-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013150/
https://www.ncbi.nlm.nih.gov/pubmed/35428319
http://dx.doi.org/10.1186/s13072-022-00442-x

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