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Microgliosis and neuronal proteinopathy in brain persist beyond viral clearance in SARS-CoV-2 hamster model

BACKGROUND: Neurological symptoms such as cognitive decline and depression contribute substantially to post-COVID-19 syndrome, defined as lasting symptoms several weeks after initial SARS-CoV-2 infection. The pathogenesis is still elusive, which hampers appropriate treatment. Neuroinflammatory respo...

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Detalles Bibliográficos
Autores principales: Käufer, Christopher, Schreiber, Cara S., Hartke, Anna-Sophia, Denden, Ivo, Stanelle-Bertram, Stephanie, Beck, Sebastian, Kouassi, Nancy Mounogou, Beythien, Georg, Becker, Kathrin, Schreiner, Tom, Schaumburg, Berfin, Beineke, Andreas, Baumgärtner, Wolfgang, Gabriel, Gülsah, Richter, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013202/
https://www.ncbi.nlm.nih.gov/pubmed/35439679
http://dx.doi.org/10.1016/j.ebiom.2022.103999