Transcriptional profiling of macrophages reveals distinct parasite stage-driven signatures during early infection by Leishmania donovani

Macrophages undergo swift changes in mRNA abundance upon pathogen invasion. Herein we describe early remodelling of the macrophage transcriptome during infection by amastigotes or promastigotes of Leishmania donovani. Approximately 10–16% of host mRNAs were differentially modulated in L. donovani-in...

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Detalles Bibliográficos
Autores principales: Chaparro, Visnu, Graber, Tyson E., Alain, Tommy, Jaramillo, Maritza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013368/
https://www.ncbi.nlm.nih.gov/pubmed/35430587
http://dx.doi.org/10.1038/s41598-022-10317-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013368/
https://www.ncbi.nlm.nih.gov/pubmed/35430587
http://dx.doi.org/10.1038/s41598-022-10317-6

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