SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRβ pathway

BACKGROUND: Excessively deposited fibrotic scar after spinal cord injury (SCI) inhibits axon regeneration. It has been reported that platelet-derived growth factor receptor beta (PDGFRβ), as a marker of fibrotic scar-forming fibroblasts, can only be activated by platelet-derived growth factor (PDGF)...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ziyu, Yu, Shuisheng, Liu, Yanchang, Hu, Xuyang, Li, Yiteng, Xiao, Zhaoming, Chen, Yihao, Tian, Dasheng, Xu, Xinzhong, Cheng, Li, Zheng, Meige, Jing, Juehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013464/
https://www.ncbi.nlm.nih.gov/pubmed/35429978
http://dx.doi.org/10.1186/s12974-022-02449-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013464/
https://www.ncbi.nlm.nih.gov/pubmed/35429978
http://dx.doi.org/10.1186/s12974-022-02449-3

Ejemplares similares