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SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRβ pathway

BACKGROUND: Excessively deposited fibrotic scar after spinal cord injury (SCI) inhibits axon regeneration. It has been reported that platelet-derived growth factor receptor beta (PDGFRβ), as a marker of fibrotic scar-forming fibroblasts, can only be activated by platelet-derived growth factor (PDGF)...

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Detalles Bibliográficos
Autores principales:	Li, Ziyu, Yu, Shuisheng, Liu, Yanchang, Hu, Xuyang, Li, Yiteng, Xiao, Zhaoming, Chen, Yihao, Tian, Dasheng, Xu, Xinzhong, Cheng, Li, Zheng, Meige, Jing, Juehua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013464/ https://www.ncbi.nlm.nih.gov/pubmed/35429978 http://dx.doi.org/10.1186/s12974-022-02449-3

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