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The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes

BACKGROUND: Elevated production of the cytokines interleukin (IL)-6 or interferon (IFN)-α in the central nervous system (CNS) is implicated in the pathogenesis of neurological diseases such as neuromyelitis optica spectrum disorders or cerebral interferonopathies, respectively. Transgenic mice with...

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Detalles Bibliográficos
Autores principales: West, Phillip K., McCorkindale, Andrew N., Guennewig, Boris, Ashhurst, Thomas M., Viengkhou, Barney, Hayashida, Emina, Jung, So Ri, Butovsky, Oleg, Campbell, Iain L., Hofer, Markus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013466/
https://www.ncbi.nlm.nih.gov/pubmed/35429976
http://dx.doi.org/10.1186/s12974-022-02441-x