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Protective association of Klotho rs495392 gene polymorphism against hepatic steatosis in non-alcoholic fatty liver disease patients

BACKGROUND/AIMS: Non-alcoholic fatty liver disease (NAFLD) is closely associated with metabolic dysfunction. Among the multiple factors, genetic variation acts as important modifiers. Klotho, an enzyme encoded by the klotho (KL) gene in human, has been implicated in the pathogenesis of metabolic dys...

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Detalles Bibliográficos
Autores principales: Liu, Wen-Yue, Zhang, Xiaofang, Li, Gang, Tang, Liang-Jie, Zhu, Pei-Wu, Rios, Rafael S., Zheng, Kenneth I., Ma, Hong-Lei, Wang, Xiao-Dong, Pan, Qiuwei, de Knegt, Robert J., Valenti, Luca, Ghanbari, Mohsen, Zheng, Ming-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013609/
https://www.ncbi.nlm.nih.gov/pubmed/34839623
http://dx.doi.org/10.3350/cmh.2021.0301