Non-viral delivery of CRISPR–Cas9 complexes for targeted gene editing via a polymer delivery system

Recent advances in molecular biology have led to the CRISPR revolution, but the lack of an efficient and safe delivery system into cells and tissues continues to hinder clinical translation of CRISPR approaches. Polymeric vectors offer an attractive alternative to viruses as delivery vectors due to...

Descripción completa

Detalles Bibliográficos
Autores principales: O’Keeffe Ahern, Jonathan, Lara-Sáez, Irene, Zhou, Dezhong, Murillas, Rodolfo, Bonafont, Jose, Mencía, Ángeles, García, Marta, Manzanares, Darío, Lynch, Jennifer, Foley, Ruth, Xu, Qian, Sigen, A, Larcher, Fernando, Wang, Wenxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013665/
https://www.ncbi.nlm.nih.gov/pubmed/34363036
http://dx.doi.org/10.1038/s41434-021-00282-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013665/
https://www.ncbi.nlm.nih.gov/pubmed/34363036
http://dx.doi.org/10.1038/s41434-021-00282-6

Ejemplares similares