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COVID-19 susceptibility, severity, clinical outcome and Toll-like receptor (7) mRNA expression driven by TLR7 gene polymorphism (rs3853839) in middle-aged individuals without previous comorbidities

BACKGROUND: Toll-like receptors are implicated in the pathophysiology of the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory disease (MERS), according to several studies. The whole-genome sequencing of SARS-CoV-2 revealed that the TLR7 gene could be implicate...

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Detalles Bibliográficos
Autores principales: El-Hefnawy, Sally M., Eid, Hanaa A., Mostafa, Rasha G., Soliman, Shaimaa S., Omar, Thoria A., Azmy, Rania M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013694/
https://www.ncbi.nlm.nih.gov/pubmed/35463461
http://dx.doi.org/10.1016/j.genrep.2022.101612