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Changes in corticostriatal connectivity and striatal tissue iron associated with efficacy of clozapine for treatment‑resistant schizophrenia

RATIONALE: Though numerous studies demonstrate the superiority of clozapine (CLZ) for treatment of persistent psychotic symptoms that are characteristic of treatment-refractory schizophrenia (TRS), what remains unknown are the neural and molecular mechanisms underlying CLZ’s efficacy. Recent work im...

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Detalles Bibliográficos
Autores principales: Blazer, Annie, Chengappa, K. N. Roy, Foran, William, Parr, Ashley C., Kahn, Charles E., Luna, Beatriz, Sarpal, Deepak K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013738/
https://www.ncbi.nlm.nih.gov/pubmed/35435461
http://dx.doi.org/10.1007/s00213-022-06138-0