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Role of Tocilizumab in Down Regulating sCD163 Plasmatic Levels in a Cohort of COVID-19 Patients

BACKGROUND: CD163, a haptoglobin-hemoglobin scavenger receptor mostly expressed by monocytes and macrophages, is involved in the regulation of inflammatory processes. Following proteolytic cleavage after pro-inflammatory stimulation, CD163 is shed from the cell surface and its soluble form in plasma...

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Detalles Bibliográficos
Autores principales: Marocco, Raffaella, Carraro, Anna, Zingaropoli, Maria Antonella, Nijhawan, Parni, Tortellini, Eeva, Guardiani, Mariasilvia, Mengoni, Fabio, Zuccalà, Paola, Belvisi, Valeria, Kertusha, Blerta, Parente, Alberico, Del Borgo, Cosmo, Vullo, Vincenzo, Ciardi, Maria Rosa, Mastroianni, Claudio Maria, Lichtner, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013773/
https://www.ncbi.nlm.nih.gov/pubmed/35444637
http://dx.doi.org/10.3389/fimmu.2022.871592