Polyglutamine Expansion in Huntingtin and Mechanism of DNA Damage Repair Defects in Huntington’s Disease

Emerging evidence suggests that DNA repair deficiency and genome instability may be the impending signs of many neurological diseases. Genome-wide association (GWAS) studies have established a strong correlation between genes that play a role in DNA damage repair and many neurodegenerative diseases,...

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Detalles Bibliográficos
Autores principales: Pradhan, Subrata, Gao, Rui, Bush, Keegan, Zhang, Nan, Wairkar, Yogesh P., Sarkar, Partha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013776/
https://www.ncbi.nlm.nih.gov/pubmed/35444517
http://dx.doi.org/10.3389/fncel.2022.837576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013776/
https://www.ncbi.nlm.nih.gov/pubmed/35444517
http://dx.doi.org/10.3389/fncel.2022.837576

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