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Salt-Sensitive Hypertension Induces Osteoclastogenesis and Bone Resorption via Upregulation of Angiotensin II Type 1 Receptor Expression in Osteoblasts

Hypertension is a chronic-low grade inflammatory disease, which is known to be associated with increased bone loss. Excessive activity of the local renin–angiotensin system (RAS) in bone leads to increased bone resorption. As inflammatory cytokines may activate RAS components, we hypothesized that t...

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Detalles Bibliográficos
Autores principales: Pramusita, Adya, Kitaura, Hideki, Ohori, Fumitoshi, Noguchi, Takahiro, Marahleh, Aseel, Nara, Yasuhiko, Kinjo, Ria, Ma, Jinghan, Kanou, Kayoko, Tanaka, Yukinori, Mizoguchi, Itaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013777/
https://www.ncbi.nlm.nih.gov/pubmed/35445013
http://dx.doi.org/10.3389/fcell.2022.816764