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Salt-Sensitive Hypertension Induces Osteoclastogenesis and Bone Resorption via Upregulation of Angiotensin II Type 1 Receptor Expression in Osteoblasts
Hypertension is a chronic-low grade inflammatory disease, which is known to be associated with increased bone loss. Excessive activity of the local renin–angiotensin system (RAS) in bone leads to increased bone resorption. As inflammatory cytokines may activate RAS components, we hypothesized that t...
Autores principales: | Pramusita, Adya, Kitaura, Hideki, Ohori, Fumitoshi, Noguchi, Takahiro, Marahleh, Aseel, Nara, Yasuhiko, Kinjo, Ria, Ma, Jinghan, Kanou, Kayoko, Tanaka, Yukinori, Mizoguchi, Itaru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013777/ https://www.ncbi.nlm.nih.gov/pubmed/35445013 http://dx.doi.org/10.3389/fcell.2022.816764 |
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